Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995584 | 0.88 | APEX1 (0.40) | APEX1KMT2ATHRBTDP1MTTP | |
| SCHEMBL11208949 | 0.83 | SIGMAR1 (0.41) | MTTP | |
| SCHEMBL11085690 | 0.81 | DRD2 (0.42) | PDK2MTTP | |
| SCHEMBL10794587 | 0.80 | APEX1 (0.41) | APEX1KMT2APDK2THRBTDP1 | |
| SCHEMBL11089773 | 0.80 | MAOA (0.49) | KMT2ATDP1 | |
| Indecainide SCHEMBL121202 | 0.79 | KDM4E (0.42) | APEX1KMT2APDK2TDP1 | |
| SCHEMBL10778218 | 0.79 | APEX1 (0.42) | APEX1KMT2APDK2THRBTDP1 | |
| SCHEMBL10779454 | 0.78 | KMT2A (0.39) | APEX1KMT2AMTTP | |
| Indecainide SCHEMBL121201 | 0.78 | KDM4E (0.41) | APEX1TDP1 | |
| Indecainide SCHEMBL29397898 | 0.78 | KDM4E (0.41) | APEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508735-A | ALSO ANESTHETIC | ELI LILLY AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |