Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | MTTP | P55157 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085690 | 0.92 | DRD2 (0.42) | MTTPKDM4E | |
| SCHEMBL10995584 | 0.92 | APEX1 (0.40) | MTTP | |
| SCHEMBL11086390 | 0.87 | PDK2 (0.36) | SIGMAR1ASAH1MTTPHDAC1HDAC2 | |
| SCHEMBL11019261 | 0.83 | APEX1 (0.36) | MTTP | |
| SCHEMBL11083125 | 0.82 | MTTP (0.36) | MTTP | |
| SCHEMBL11083128 | 0.82 | MTTP (0.36) | MTTP | |
| SCHEMBL11083146 | 0.81 | PDK2 (0.36) | MTTP | |
| SCHEMBL11087470 | 0.80 | ICMT (0.47) | MTTP | |
| SCHEMBL11089773 | 0.80 | MAOA (0.49) | SIGMAR1HDAC1HDAC2 | |
| Indecainide SCHEMBL121202 | 0.80 | KDM4E (0.42) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018076-B1 | 9-AMINOALKYLFLUORENES, PROCESS THEREFOR AND ANTIARRHYTHMIC FORMULATIONS THEREOF | ELI LILLY AND COMPANY (US) | 1983-09-21 | — | — | EP | disclosed |
| EP-0018076-A1 | 9-Aminoalkylfluorenes, process therefor and antiarrhythmic formulations thereof | ELI LILLY AND COMPANY (US) | 1980-10-29 | — | — | EP | disclosed |