Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648825 | 0.78 | AKR1C3 (0.49) | AKR1C3AKR1C2GAAMAPTMEN1 | |
| SCHEMBL10938004 | 0.76 | MEN1 (0.56) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL12866555 | 0.76 | MAPT (0.48) | AKR1C3AKR1C2GAAMAPTMEN1 | |
| SCHEMBL9702575 | 0.75 | TUBB4A (0.48) | AKR1C3AKR1C2GAATUBB4ATUBB | |
| SCHEMBL11018690 | 0.74 | MAPT (0.46) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10930468 | 0.74 | GAA (0.64) | AKR1C3AKR1C2GAAMAPTMEN1 | |
| SCHEMBL10834390 | 0.73 | MEN1 (0.77) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL10934839 | 0.73 | MEN1 (0.60) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL10939818 | 0.73 | MEN1 (0.60) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL7256133 | 0.73 | MAPT (0.77) | GAATUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496590-A | TREATMENT OR PREVENTION OF ALLERGIC ASTHMA, ANTI-ASTHMATIC | STERLING DRUG INC. (US) | 1985-01-29 | — | — | US | claimed |
| US-4496590-A | TREATMENT OR PREVENTION OF ALLERGIC ASTHMA, ANTI-ASTHMATIC | STERLING DRUG INC. (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0122518-A1 | Phenylaminobenzenealkanols and preparation | STERLING DRUG INC. (US) | 1984-10-24 | — | — | EP | disclosed |