Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648823 | 0.84 | MAPT (0.48) | MAPTRAB9AGAAMAPK1TDP1 | |
| SCHEMBL12648825 | 0.83 | AKR1C3 (0.49) | MAPTRAB9AGAAMAPK1TDP1 | |
| SCHEMBL12881308 | 0.80 | ALDH1A1 (0.49) | MAPTRAB9AGAAMAPK1TDP1 | |
| SCHEMBL10930468 | 0.76 | GAA (0.64) | MAPTRAB9AGAAMAPK1TDP1 | |
| SCHEMBL11019297 | 0.76 | AKR1C3 (0.44) | MAPTRAB9AGAAMAPK1TDP1 | |
| SCHEMBL15960962 | 0.76 | RAB9A (0.50) | MAPTRAB9AGAAMAPK1TDP1 | |
| SCHEMBL12595509 | 0.76 | ADRB2 (0.44) | MAPTRAB9AGAAMAPK1TDP1 | |
| SCHEMBL12190542 | 0.74 | TYR (0.40) | MAPTRAB9AGAAMAPK1TDP1 | |
| SCHEMBL12648781 | 0.74 | MAPT (0.43) | MAPTRAB9AGAAMAPK1TDP1 | |
| SCHEMBL25634740 | 0.73 | GAA (0.80) | MAPTRAB9AGAAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7894695-B2 | Tricyclic spacer systems for nonlinear optical devices | LIGHTWAVE LOGIC, INC. | 2011-02-22 | — | — | US | disclosed |
| US-20080009620-A1 | Tricyclic Spacer Systems For Nonlinear Optical Devices | THIRD-ORDER NANOTECHNOLOGIES, INC. (US) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009620-A1 | Tricyclic Spacer Systems For Nonlinear Optical Devices | AQP4, CCND3, CDK14 | MAPT 2297/4885RAB9A 4176/4885GAA 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.