Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PDE5A | O76074 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221333 | 0.75 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL11223282 | 0.75 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL7444582 | 0.75 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL15883192 | 0.74 | TBXAS1 (0.64) | TBXAS1 | |
| SCHEMBL1000759 | 0.72 | GAA (0.82) | POLBMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6877987 | 0.72 | GAA (0.59) | POLBMEN1KMT2AGAALMNA | |
| SCHEMBL10113608 | 0.71 | POLB (0.53) | POLBMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10113884 | 0.71 | POLB (0.53) | POLBMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28803096 | 0.71 | ALDH1A1 (0.56) | POLBMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4968797 | 0.70 | SMN1; SMN2 (0.65) | POLBMEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60013773-A | — | — | None | — | — | JP | disclosed |
| JP-S6013773-A | 2-SUBSTITUTED-AMINO-4-THIAZOLYLACETIC ACID AND ITS LOWER ALKYL ESTER | YAMANOUCHI PHARMACEUT CO LTD | 1985-01-24 | — | — | JP | disclosed |