SCHEMBL110198

SCHEMBL110198

O=C(O)Cc1ccc(CO)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.65
CAMK2A Q9UQM7 1/20 0.65
AKR1B1 P15121 1/20 0.64
TSHR P16473 3/20 0.60
LMNA P02545 2/20 0.60
GAA P10253 2/20 0.60
ABCC4 O15439 1/20 0.60
PTGS1 P23219 1/20 0.60
HTT P42858 1/20 0.60
KLKB1 P03952 1/20 0.55
CTSB P07858 1/20 0.55
HPGD P15428 3/20 0.54
HSD17B10 Q99714 3/20 0.54
ALDH1A1 P00352 3/20 0.54
FFAR1 O14842 1/20 0.54
POLB P06746 2/20 0.52
KDM4E B2RXH2 2/20 0.52
MAPT P10636 2/20 0.52
RGS12 O14924 1/20 0.52
NFKB1 P19838 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69614 0.89 CA2 (0.79) CA2CAMK2AAKR1B1TSHRLMNA
Hydrochloric Acid SCHEMBL6765874 0.86 CA2 (0.75) CA2CAMK2AAKR1B1TSHRLMNA
Hydrochloric Acid SCHEMBL25180348 0.86 CA2 (0.75) CA2CAMK2AAKR1B1TSHRLMNA
SCHEMBL68027 0.81 LMNA (0.86) CA2CAMK2AAKR1B1TSHRLMNA
SCHEMBL2996429 0.81 CA2 (0.68) CA2CAMK2AAKR1B1TSHRLMNA
SCHEMBL18427891 0.81 LMNA (0.86) CA2CAMK2AAKR1B1TSHRLMNA
Oxalic Acid SCHEMBL30089202 0.80 TSHR (0.58) CA2CAMK2ATSHRALDH1A1TDP1
SCHEMBL23501410 0.80 ALDH1A1 (0.61) CA2CAMK2AAKR1B1TSHRLMNA
SCHEMBL21585550 0.80 PTGS1 (0.62) CA2CAMK2AAKR1B1TSHRLMNA
SCHEMBL2642144 0.79 CA2 (0.65) CA2CAMK2AAKR1B1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843276-B Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-11-26 CN claimed
CN-115536517-B Preparation method of 4-hydroxymethylphenylacetic acid 苏州昊帆生物股份有限公司 2024-08-02 CN claimed
CN-117843276-A Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-04-09 CN claimed
CN-116675459-A Preparation method of cementing material reinforcing agent with high compressive strength 泉州市富霸新型材料科技发展有限公司 2023-09-01 CN claimed
CN-115536517-A Preparation method of 4-hydroxymethyl phenylacetic acid 苏州昊帆生物股份有限公司 2022-12-30 CN claimed
CN-114805601-A Application of polypeptide analogue in anti-wrinkle and anti-aging 深圳深创生物药业有限公司 2022-07-29 CN claimed
CN-113121436-B Preparation method of nertadalal dimethyl sulfonate 江苏艾立康医药科技有限公司 2022-03-08 CN claimed
CN-113121436-A Preparation method of nertadalal dimethyl sulfonate 江苏艾立康医药科技有限公司 2021-07-16 CN claimed
CN-112409445-A Solid-phase synthesis method of snake venom-like tripeptide 浙江湃肽生物有限公司 2021-02-26 CN claimed
US-10906933-B2 Coupled peptide chain for dissolving poorly soluble polypeptides and application thereof for separation and purification in liquid chromatography SPEC-CHEM INDUSTRY INC. (CN) 2021-02-02 US claimed
CN-101911914-A Culture medium for spore germination and seedling culturing of pteridophyte UNIV CHINA GEOSCIENCES WUHAN 2010-12-15 CN claimed
US-7166696-B2 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-01-23 US claimed
US-20040265899-A1 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY 2004-12-30 US claimed
US-6787635-B2 azlactone-functionalized support such as a crosslinked polymer containing an alkenyl azlactone; use making combinatorial libraries 3M INNOVATIVE PROPERTIES COMPANY 2004-09-07 US claimed
EP-1373167-A2 SOLID PHASE SYNTHESIS SUPPORTS AND METHODS 3M Innovative Properties Company (US) 2004-01-02 EP claimed
US-20020173051-A1 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY 2002-11-21 US claimed
WO-2002081078-A2 SOLID PHASE SYNTHESIS SUPPORTS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-10-17 WO claimed
WO-1996030392-A1 PROCESS FOR THE PRODUCTION OF COMBINATORIAL COMPOUND LIBRARIES NOVARTIS AG (CH) 1996-10-03 WO claimed
EP-0733213-A1 PROCESS FOR THE PRODUCTION OF COMBINATORIAL COMPOUND LIBRARIES Novartis AG (CH) 1996-09-25 EP claimed
WO-1995016209-A1 PROCESS FOR THE PRODUCTION OF COMBINATORIAL COMPOUND LIBRARIES CIBA-GEIGY AG (CH) 1995-06-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173051-A1 Solid phase synthesis supports and methods FES, LSS, CCNK CA2 4783/4885CAMK2A 4296/4885AKR1B1 2431/4885
US-20040265899-A1 Solid phase synthesis supports and methods FES, LSS, CCNK CA2 4783/4885CAMK2A 4296/4885AKR1B1 2431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.