Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23117237 | 0.88 | PNMT (0.41) | PNMTSLC6A2SLC6A3CHRNB2CHRNB4 | |
| SCHEMBL9667411 | 0.78 | CHRNB2 (0.37) | PNMTBACE1BACE2SLC6A2SLC6A3 | |
| SCHEMBL11020140 | 0.76 | ADRA2B (0.43) | NOTUMLMNANPSR1BACE1BACE2 | |
| SCHEMBL10772065 | 0.74 | — | — | |
| SCHEMBL9212549 | 0.74 | CYP2C9 (0.42) | PNMTSLC6A2SLC6A3CHRNB2CHRNB4 | |
| SCHEMBL23532453 | 0.73 | CHRNB2 (0.39) | PNMTSLC6A2SLC6A3CHRNB2CHRNB4 | |
| SCHEMBL9214306 | 0.73 | GABRA1 (0.32) | SLC6A2SLC6A3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9792509 | 0.71 | NOTUM (0.39) | NOTUMLMNANPSR1BACE1BACE2 | |
| SCHEMBL4376737 | 0.70 | PNMT (0.45) | PNMTLMNASLC6A2SLC6A3CHRNB2 | |
| SCHEMBL8929733 | 0.68 | SLC6A2 (0.43) | SLC6A2SLC6A3CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057504-A | PESTICIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-15 | — | — | US | disclosed |
| EP-0243184-A2 | Pesticidal compounds | ROUSSEL-UCLAF (FR) | 1987-10-28 | — | — | EP | disclosed |