Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923503 | 0.83 | KMT2A (0.46) | KMT2AUSP2ABCB11PTGS2TSHR | |
| SCHEMBL7682322 | 0.79 | THRB (0.48) | KMT2AUSP2ABCB11PTGS2THRB | |
| SCHEMBL11084402 | 0.77 | USP2 (0.52) | KMT2AUSP2THRBTSHRLMNA | |
| SCHEMBL7683947 | 0.77 | PTGS2 (0.50) | KMT2AUSP2ABCB11PTGS2THRB | |
| SCHEMBL7678485 | 0.76 | KMT2A (0.48) | KMT2AUSP2PTGS2THRBTSHR | |
| SCHEMBL7684715 | 0.76 | LMNA (0.42) | KMT2AABCB11PTGS2THRBLMNA | |
| SCHEMBL10920481 | 0.74 | TSHR (0.47) | KMT2AUSP2TSHRLMNAMEN1 | |
| SCHEMBL7675435 | 0.74 | PTGS2 (0.57) | KMT2AABCB11PTGS2THRBTSHR | |
| SCHEMBL11015971 | 0.74 | SRD5A2 (0.50) | KMT2AUSP2ABCB11PTGS2THRB | |
| SCHEMBL7678256 | 0.72 | PTGS2 (0.46) | KMT2AUSP2ABCB11PTGS2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152542-A1 | Pyrrol-3-carboxylic acids having central analgesic activity | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1985-08-28 | — | — | EP | disclosed |