Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020534 | 0.83 | POLB (0.54) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL1306664 | 0.82 | RAB9A (0.50) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL10646050 | 0.71 | GRIN2D (0.41) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| Neltenexine SCHEMBL20299 | 0.71 | CYP1A2 (0.51) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| Neltenexine SCHEMBL10650927 | 0.71 | CYP3A4 (0.52) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| Neltenexine SCHEMBL15673426 | 0.71 | CYP3A4 (0.52) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL28844856 | 0.71 | KMT2A (0.74) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL29684523 | 0.71 | KMT2A (0.74) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL25351544 | 0.70 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL30535354 | 0.70 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150787-A2 | Compound having antibronchopneumopathic activity, process for its preparation and pharmaceutical compositions containing it | PULITZER ITALIANA S.p.A. (IT) | 1985-08-07 | — | — | EP | claimed |