Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GAPDH | P04406 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020529 | 0.83 | RAB9A (0.50) | POLBSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL1306664 | 0.82 | RAB9A (0.50) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL28857621 | 0.79 | GPR174 (0.69) | POLBSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL19476108 | 0.77 | SMN1; SMN2 (0.61) | POLBSMN1; SMN2NPC1RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL11019226 | 0.73 | RAB9A (0.40) | POLBSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL8456040 | 0.72 | KMT2A (0.56) | POLBSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL21979989 | 0.72 | ALDH1A1 (0.45) | KMT2AMEN1MAPT | |
| SCHEMBL31218457 | 0.72 | ALDH1A1 (0.45) | KMT2AMEN1MAPT | |
| SCHEMBL1868108 | 0.71 | KDM4E (0.61) | POLBSMN1; SMN2NPC1RAB9AKMT2A | |
| Neltenexine SCHEMBL10650927 | 0.71 | CYP3A4 (0.52) | SMN1; SMN2NPC1RAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150787-A2 | Compound having antibronchopneumopathic activity, process for its preparation and pharmaceutical compositions containing it | PULITZER ITALIANA S.p.A. (IT) | 1985-08-07 | — | — | EP | claimed |