Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | REN | P00797 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 9/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17326876 | 0.91 | CTSS (0.56) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL7315478 | 0.89 | CTSS (0.59) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL11699180 | 0.89 | CTSS (0.55) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL5717952 | 0.88 | CTSK (0.63) | CTSSCTSKCA2 | |
| SCHEMBL6623782 | 0.88 | CTSK (0.63) | CTSSCTSKCA2 | |
| SCHEMBL6623780 | 0.88 | CTSK (0.63) | CTSSCTSKCA2 | |
| SCHEMBL10787765 | 0.88 | CTSS (0.55) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL10787770 | 0.88 | CTSS (0.55) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL11181475 | 0.86 | CTSK (0.59) | CTSSCTSKRENBACE1CA2 | |
| SCHEMBL10727619 | 0.86 | CTSS (0.62) | CTSSCTSKRENCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260130889-A1 | MICROTUBULE POLYMERIZATION INHIBITOR PRODRUGS AND METHODS OF USING THE SAME | UNIV MARYLAND (US) | 2026-05-14 | — | — | US | disclosed |
| US-12433873-B2 | Microtubule polymerization inhibitor prodrugs and methods of using the same | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2025-10-07 | — | — | US | disclosed |
| EP-4403171-A2 | MICROTUBULE POLYMERIZATION INHIBITOR PRODRUGS AND METHODS OF USING THE SAME | University of Maryland, Baltimore (US) | 2024-07-24 | — | — | EP | disclosed |
| EP-3641741-B1 | MICROTUBULE POLYMERIZATION INHIBITOR PRODRUGS AND METHODS OF USING THE SAME | UNIV MARYLAND (US) | 2024-03-20 | — | — | EP | disclosed |
| US-20230241034-A1 | MICROTUBULE POLYMERIZATION INHIBITOR PRODRUGS AND METHODS OF USING THE SAME | UNIV MARYLAND (US) | 2023-08-03 | — | — | US | disclosed |
| US-11622960-B2 | Microtubule polymerization inhibitor prodrugs and methods of using the same | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-04-11 | — | — | US | disclosed |
| EP-0161007-A2 | Retro - inverso C-Terminal hexapeptide analogues of substance P | ENI-Ente Nazionale Idrocarburi (IT) | 1985-11-13 | — | — | EP | disclosed |
| EP-0082568-B1 | RETRO-INVERSO ANALOGUES OF C-TERMINAL PENTA AND HEXAPEPTIDES OF SUBSTANCE P. | ANIC S.p.A. (IT) | 1984-11-21 | — | — | EP | disclosed |
| US-4439360-A | Retro-inverso analogues of C-terminal penta and hexapeptides of Substance P | ANIC S.P.A. (IT) | 1984-03-27 | — | — | US | disclosed |
| EP-0082568-A2 | Retro-inverso analogues of C-terminal penta and hexapeptides of substance P. | ANIC S.p.A. (IT) | 1983-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11622960-B2 | Microtubule polymerization inhibitor prodrugs and methods of using the same | TUBA1C, TUBB3, TUBB | CTSS 1741/4885CTSK 2183/4885REN 2087/4885 |
| US-12433873-B2 | Microtubule polymerization inhibitor prodrugs and methods of using the same | TUBA1C, TUBB3, TUBB | CTSS 1741/4885CTSK 2183/4885REN 2087/4885 |
| US-20230241034-A1 | MICROTUBULE POLYMERIZATION INHIBITOR PRODRUGS AND METHODS OF USING THE SAME | TUBA1C, TUBB3, TUBB | CTSS 1741/4885CTSK 2183/4885REN 2087/4885 |
| US-20260130889-A1 | MICROTUBULE POLYMERIZATION INHIBITOR PRODRUGS AND METHODS OF USING THE SAME | TUBB3, TUBB1, TUBB | CTSS 1380/4885CTSK 810/4885REN 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.