Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690389 | 0.75 | SMN1; SMN2 (0.70) | SMN1; SMN2HCRTR1TP53MAPTALOX15 | |
| SCHEMBL10692304 | 0.74 | KMT2A (0.43) | SMN1; SMN2HCRTR1TP53MAPTALOX15 | |
| SCHEMBL10692769 | 0.72 | MAPK1 (0.39) | SMN1; SMN2HCRTR1TP53MAPTALOX15 | |
| SCHEMBL10692077 | 0.71 | CYP1A2 (0.42) | SMN1; SMN2HCRTR1TP53MAPTALOX15 | |
| SCHEMBL10693417 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2HCRTR1TP53MAPTALOX15 | |
| SCHEMBL10691237 | 0.69 | SMN1; SMN2 (0.36) | SMN1; SMN2HCRTR1TP53MAPTALOX15 | |
| SCHEMBL10690457 | 0.69 | NR4A2 (0.42) | SMN1; SMN2HCRTR1TP53MAPTALOX15 | |
| SCHEMBL10692146 | 0.69 | NOTUM (0.36) | SMN1; SMN2HCRTR1TP53MAPTALOX15 | |
| SCHEMBL10693751 | 0.69 | ATP4A (0.44) | SMN1; SMN2HCRTR1TP53MAPTALOX15 | |
| SCHEMBL10690142 | 0.68 | ALDH1A1 (0.49) | SMN1; SMN2HCRTR1TP53MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |