Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022136 | 0.92 | MAPT (0.39) | HPSEMAPTLMNAGAAAGPAT2 | |
| SCHEMBL11020057 | 0.85 | CHEK2 (0.46) | PDE7AHPSEPDE2ACOMTSCD | |
| SCHEMBL11022200 | 0.84 | ABL1 (0.41) | HPSEMAPTLMNAGAAAGPAT2 | |
| SCHEMBL11018765 | 0.83 | SCD (0.41) | LMNAPDE2AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL10746057 | 0.83 | PDE7A (0.43) | PDE7AHPSEMAPTPDE2AKMT2A | |
| SCHEMBL11019245 | 0.82 | CHEK2 (0.44) | MAPTPDE2ANPC1POLBNPSR1 | |
| SCHEMBL11020236 | 0.81 | CHEK2 (0.48) | PDE2A | |
| SCHEMBL11036642 | 0.81 | PDE2A (0.41) | PDE2AKDM4ECOMTSCD | |
| SCHEMBL11020063 | 0.80 | CHEK2 (0.56) | PDE7APOLBSCD | |
| SCHEMBL11018830 | 0.80 | PDE2A (0.44) | PDE7AHPSELMNAPDE2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |