Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4562595 | 0.83 | AKR1C2 (0.48) | TRPV1AKR1C2PDGFRBFGFR1KDR | |
| SCHEMBL5305951 | 0.79 | AKR1C2 (0.49) | TRPV1AKR1C2PDGFRBFGFR1KDR | |
| SCHEMBL8796396 | 0.79 | TRPV1 (0.46) | TRPV1AKR1C2PDGFRBFGFR1KDR | |
| SCHEMBL8978361 | 0.78 | TRPV1 (0.42) | TRPV1AKR1C2PDGFRBFGFR1KDR | |
| SCHEMBL8978296 | 0.77 | PDGFRB (0.42) | TRPV1AKR1C2PDGFRBFGFR1KDR | |
| SCHEMBL25260242 | 0.77 | ALDH1A1 (0.58) | AKR1C2PDGFRBFGFR1KDRMEN1 | |
| SCHEMBL10637946 | 0.76 | PIKFYVE (0.42) | TRPV1AKR1C2PDGFRBFGFR1KDR | |
| SCHEMBL8978368 | 0.76 | ALDH1A1 (0.41) | TRPV1AKR1C2PDGFRBFGFR1KDR | |
| SCHEMBL8978300 | 0.76 | PDGFRB (0.40) | TRPV1AKR1C2PDGFRBFGFR1KDR | |
| SCHEMBL8686345 | 0.75 | TRPV1 (0.50) | TRPV1AKR1C2PDGFRBFGFR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163286-A2 | Acylated sugars, method for their preparation and their use | CIBA-GEIGY AG (CH) | 1985-12-04 | — | — | EP | claimed |