Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288766 | 0.99 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2THRBKDM4ENPSR1 | |
| SCHEMBL11018161 | 0.99 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2THRBKDM4ENPSR1 | |
| SCHEMBL7428692 | 0.96 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2THRBKDM4ENPSR1 | |
| SCHEMBL11203221 | 0.90 | THRB (0.43) | ALDH1A1SMN1; SMN2THRBKDM4ENPSR1 | |
| SCHEMBL7431979 | 0.88 | HDAC1 (0.41) | KDM4EALOX5KMT2AMEN1MAOB | |
| SCHEMBL11205844 | 0.88 | MAPT (0.45) | ALDH1A1SMN1; SMN2THRBKDM4ENPSR1 | |
| SCHEMBL11294373 | 0.85 | MAPT (0.48) | ALDH1A1SMN1; SMN2THRBKDM4ENPSR1 | |
| SCHEMBL6265451 | 0.84 | L3MBTL1 (0.46) | ALDH1A1KDM4EMAPTALOX5KMT2A | |
| SCHEMBL7485729 | 0.84 | LMNA (0.39) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL11295197 | 0.84 | MAPT (0.50) | ALDH1A1SMN1; SMN2THRBKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |
| WO-1982000643-A1 | SUBSTITUTED OXIRANECARBONIC ACIDS,PREPARATION AND PHARMACEUTICAL UTILISATION THEREOF | BYK GULDEN LOMBERG CHEM FAB (DE) | 1982-03-04 | — | — | WO | disclosed |