Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021941 | 0.85 | TBXAS1 (0.47) | TBXAS1FFAR1HTR2CSMN1; SMN2NR1H4 | |
| SCHEMBL2536496 | 0.81 | KMT2A (0.54) | TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL7388461 | 0.81 | TBXAS1 (0.56) | TBXAS1HRH1CCR3 | |
| SCHEMBL29996269 | 0.80 | TBXAS1 (0.52) | TBXAS1FFAR1HRH1CCR3 | |
| SCHEMBL1070542 | 0.80 | CYP11B1 (0.55) | TBXAS1HRH1CCR3CYP11B1CYP11B2 | |
| SCHEMBL2908379 | 0.80 | TBXAS1 (0.52) | TBXAS1FFAR1HRH1CCR3 | |
| SCHEMBL13684905 | 0.80 | TBXAS1 (0.55) | TBXAS1FFAR1HRH1CCR3SMN1; SMN2 | |
| SCHEMBL20552139 | 0.80 | TBXAS1 (0.55) | TBXAS1HRH1CCR3SMN1; SMN2 | |
| SCHEMBL10289405 | 0.79 | TSHR (0.57) | TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL3523783 | 0.78 | TAAR1 (0.57) | TBXAS1HRH1CCR3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | disclosed |
| EP-2520566-A1 | New Pharmaceutical Compounds | Orion Corporation (FI) | 2012-11-07 | — | — | EP | disclosed |