Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724308 | 0.81 | MAPK1 (0.51) | ALDH1A1KDM4EKDM4AEGLN1L3MBTL1 | |
| SCHEMBL10347831 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EKDM4AEGLN1L3MBTL1 | |
| SCHEMBL2012449 | 0.79 | HCAR3 (0.45) | ALDH1A1KDM4ERAB9AALOX15HPGD | |
| SCHEMBL30622603 | 0.79 | HCAR3 (0.45) | ALDH1A1KDM4ERAB9AALOX15HPGD | |
| SCHEMBL16610475 | 0.76 | GRM2 (0.40) | ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL2616547 | 0.71 | HCAR3 (0.53) | ALDH1A1KDM4EL3MBTL1RAB9ATSHR | |
| SCHEMBL30144927 | 0.69 | PARP1 (0.47) | DHODHMAPK1PARP1 | |
| SCHEMBL22773113 | 0.68 | KDM4E (0.37) | ALDH1A1KDM4ETSHRTDP1MAPT | |
| SCHEMBL28279790 | 0.68 | NR4A1 (0.46) | ALDH1A1KDM4EKDM4AEGLN1L3MBTL1 | |
| SCHEMBL16246424 | 0.67 | EGLN1 (0.43) | ALDH1A1KDM4EKDM4AEGLN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057160-B1 | 2-(2-HYDROXYPHENYL)-BENZOTRIAZOLES, THEIR USE AS ULTRAVIOLET STABILIZERS AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |