SCHEMBL11022243

SCHEMBL11022243

O=C(NC(=O)c1ccccc1Cl)Nc1ccc(Oc2ccc(C(F)(F)C(F)(F)C(F)(F)F)cn2)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.56
KMT2A Q03164 2/20 0.54
POLB P06746 2/20 0.54
MEN1 O00255 1/20 0.54
LMNA P02545 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
GRM8 O00222 1/20 0.48
GRM7 Q14831 1/20 0.48
GRM4 Q14833 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PNLIP P16233 3/20 0.46
RORC P51449 1/20 0.44
PYGL P06737 2/20 0.43
BRAF P15056 1/20 0.43
KDR P35968 1/20 0.43
MAPK14 Q16539 1/20 0.43
TNNI3K Q59H18 1/20 0.43
PLCG2 P16885 1/20 0.43
NPC1 O15118 2/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9628562 0.91 KMT2A (0.66) GCGRKMT2APOLBMEN1LMNA
SCHEMBL10353936 0.82 GCGR (0.63) GCGRKMT2APOLBMEN1LMNA
SCHEMBL10495588 0.80 KMT2A (0.56) GCGRKMT2APOLBMEN1LMNA
SCHEMBL11575043 0.80 PYGL (0.52) GCGRKMT2APOLBMEN1LMNA
SCHEMBL8659667 0.78 GCGR (0.60) GCGRKMT2APOLBMEN1LMNA
SCHEMBL11248757 0.78 GCGR (0.59) GCGRKMT2APOLBMEN1LMNA
SCHEMBL10353629 0.77 GCGR (0.67) GCGRKMT2APOLBMEN1GRM8
SCHEMBL11256032 0.77 GCGR (0.58) GCGRKMT2APOLBMEN1LMNA
SCHEMBL10353871 0.76 GCGR (0.71) GCGRKMT2APOLBMEN1GRM8
SCHEMBL14227559 0.76 KMT2A (0.65) KMT2APOLBMEN1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60237066-A None JP disclosed
JP-S60237066-A N-BENZOYL-N'-PYRIDYLOXYPHENYLUREA BASED COMPOUND AND INSECTICIDE CONTAINING SAME ISHIHARA SANGYO KAISHA LTD 1985-11-25 JP disclosed