Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011927 | 0.84 | CPB2 (0.43) | TSHRSMN1; SMN2CPB2KDM4EHDAC1 | |
| SCHEMBL10969381 | 0.84 | TSHR (0.40) | TSHRSMN1; SMN2CPB2NAMPTKDM4E | |
| SCHEMBL11035308 | 0.79 | SMN1; SMN2 (0.36) | TSHRSMN1; SMN2CPB2KDM4EPOLB | |
| SCHEMBL12241782 | 0.79 | TBXAS1 (0.54) | TSHRSMN1; SMN2CPB2CPA1HDAC1 | |
| SCHEMBL11076008 | 0.79 | CPB2 (0.36) | CPB2CPA1KDM4EHDAC6MEN1 | |
| SCHEMBL31754263 | 0.78 | HSD17B10 (0.57) | TSHRSMN1; SMN2CPB2KDM4EMEN1 | |
| SCHEMBL26009155 | 0.78 | HSD17B10 (0.57) | TSHRSMN1; SMN2CPB2KDM4EMEN1 | |
| SCHEMBL31073988 | 0.78 | HSD17B10 (0.57) | TSHRSMN1; SMN2CPB2KDM4EMEN1 | |
| SCHEMBL28741563 | 0.78 | HSD17B10 (0.57) | TSHRSMN1; SMN2CPB2KDM4EMEN1 | |
| SCHEMBL10740513 | 0.77 | CPB2 (0.40) | CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070185-B1 | PREPARATION OF LOWER ALKYL 2-FORMYL-3-(6-METHYL-3-PYRIDINYL)-PROPIONATES | SMITHKLINE BECKMAN CORPORATION (US) | 1985-04-10 | — | — | EP | disclosed |
| EP-0087274-A2 | Pyrimidone derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-08-31 | — | — | EP | disclosed |
| EP-0070185-A1 | Preparation of lower alkyl 2-formyl-3-(6-methyl-3-pyridinyl)-propionates | SMITHKLINE BECKMAN CORPORATION (US) | 1983-01-19 | — | — | EP | disclosed |