Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 9/20 | 0.36 |
| ▸ | CPA1 | P15085 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | CPB1 | P15086 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080782 | 0.85 | CPB2 (0.38) | CPB2HDAC3HDAC6MEN1KMT2A | |
| SCHEMBL11022295 | 0.79 | TSHR (0.46) | CPB2CPA1HDAC6MEN1KMT2A | |
| SCHEMBL11078876 | 0.73 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11076247 | 0.71 | P4HTM (0.54) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7005064 | 0.70 | GRN (0.39) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL9900895 | 0.70 | LDHA (0.36) | CPB2CPA1 | |
| SCHEMBL11955565 | 0.69 | HRH3 (0.47) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10740513 | 0.69 | CPB2 (0.40) | CPB2CPB1 | |
| SCHEMBL1713633 | 0.68 | HCAR3 (0.55) | KDM4EALDH1A1MAPTCYP2C19 | |
| SCHEMBL7395620 | 0.68 | P4HTM (0.57) | HDAC3HDAC6MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039989-B1 | PYRIMIDONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-08-29 | — | — | EP | disclosed |
| US-4388317-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-06-14 | — | — | US | disclosed |
| EP-0039989-A1 | Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-11-18 | — | — | EP | disclosed |