Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011927 | 0.87 | CPB2 (0.43) | SMN1; SMN2TSHRPOLBCYP3A4CPB2 | |
| SCHEMBL10969381 | 0.84 | TSHR (0.40) | SMN1; SMN2TSHRPOLBCYP3A4CPB2 | |
| SCHEMBL10660485 | 0.82 | CPB2 (0.40) | SMN1; SMN2TSHRPOLBCYP3A4CPB2 | |
| SCHEMBL11235663 | 0.81 | FDPS (0.43) | POLBCYP3A4KMT2AMAPTKDM4E | |
| SCHEMBL11022295 | 0.79 | TSHR (0.46) | SMN1; SMN2TSHRPOLBCPB2KMT2A | |
| SCHEMBL10646874 | 0.76 | CYP3A4 (0.47) | SMN1; SMN2TSHRCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL10663309 | 0.75 | TSHR (0.45) | SMN1; SMN2TSHRPOLBCYP3A4KDM4E | |
| SCHEMBL10850760 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRPOLBCYP3A4CPB2 | |
| SCHEMBL10662468 | 0.73 | P2RX7 (0.39) | SMN1; SMN2TSHRCYP3A4KMT2AMAPT | |
| SCHEMBL10741906 | 0.73 | ACACB (0.40) | SMN1; SMN2CPB2KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070185-B1 | PREPARATION OF LOWER ALKYL 2-FORMYL-3-(6-METHYL-3-PYRIDINYL)-PROPIONATES | SMITHKLINE BECKMAN CORPORATION (US) | 1985-04-10 | — | — | EP | disclosed |
| EP-0070185-A1 | Preparation of lower alkyl 2-formyl-3-(6-methyl-3-pyridinyl)-propionates | SMITHKLINE BECKMAN CORPORATION (US) | 1983-01-19 | — | — | EP | disclosed |