Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209012 | 0.82 | SRD5A2 (0.46) | MEN1CYP1A2KMT2ASRD5A2ALDH1A1 | |
| SCHEMBL27876225 | 0.81 | KIF11 (0.45) | MEN1KMT2ASRD5A2RXRARXRB | |
| SCHEMBL2574861 | 0.81 | ESR1 (0.44) | ALDH1A1TSHRCA1CA2 | |
| SCHEMBL28205756 | 0.80 | KCNN4 (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11024100 | 0.78 | KIF11 (0.38) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28149485 | 0.77 | LMNA (0.33) | MEN1CYP1A2KMT2AALDH1A1MAPT | |
| SCHEMBL18394270 | 0.76 | GAA (0.41) | MEN1CYP1A2KMT2AALDH1A1TP53 | |
| SCHEMBL28113310 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL11022686 | 0.74 | CLK4 (0.42) | KMT2AMAPT | |
| SCHEMBL28741621 | 0.74 | MEN1 (0.54) | MEN1CYP1A2KMT2ASRD5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471366-B | 17-hydroxy-17-pentafluoroethylestra-4, 9(10) -diene 11-benzylidene derivatives, process for preparing them and their use for treating diseases | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-16 | — | — | CN | disclosed |
| CN-102471366-A | 17-hydroxy-17-pentafluoroethylestra-4, 9(10) -diene 11-benzylidene derivatives, process for preparing them and their use for treating diseases | BAYER SCHERING PHARMA AG | 2012-05-23 | — | — | CN | disclosed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| CN-1950372-A | imidazopyridine compounds | BANYU PHARMA CO LTD (JP) | 2007-04-18 | — | — | CN | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |