Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574861 | 0.81 | ESR1 (0.44) | LMNAHPGDCA1CA2CA9 | |
| SCHEMBL8486558 | 0.79 | — | — | |
| SCHEMBL11024100 | 0.79 | KIF11 (0.38) | NPC1HPGDRAB9AMAPTALDH1A1 | |
| SCHEMBL4689119 | 0.77 | MEN1 (0.46) | MEN1MAPTKMT2ACA1CA2 | |
| SCHEMBL11022686 | 0.75 | CLK4 (0.42) | MAPTKMT2AGAAPOLB | |
| SCHEMBL11019919 | 0.73 | CLK4 (0.30) | — | |
| SCHEMBL17069691 | 0.72 | CYP2A6 (0.35) | LMNANPSR1NPC1HPGDRAB9A | |
| SCHEMBL4573159 | 0.72 | CYP2A6 (0.35) | LMNANPSR1NPC1HPGDRAB9A | |
| SCHEMBL11019513 | 0.72 | ALDH1A1 (0.36) | NPSR1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL11026542 | 0.72 | NPC1 (0.35) | LMNANPC1HPGDRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106631983-A | Toluylene-unit-based dendritic compound and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2017-05-10 | — | — | CN | disclosed |