Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022228 | 0.95 | SIGMAR1 (0.50) | SIGMAR1KCNH2DRD2DRD4OPRM1 | |
| SCHEMBL11025496 | 0.83 | SIGMAR1 (0.50) | SIGMAR1DRD2DRD4DRD3FDPS | |
| SCHEMBL11022687 | 0.81 | SIGMAR1 (0.58) | SIGMAR1FDPS | |
| SCHEMBL11022701 | 0.80 | SIGMAR1 (0.53) | SIGMAR1KCNH2DRD2DRD4OPRM1 | |
| SCHEMBL11022689 | 0.78 | CYP1A2 (0.36) | SIGMAR1KCNH2 | |
| SCHEMBL11022231 | 0.76 | SIGMAR1 (0.65) | SIGMAR1KCNH2FDPS | |
| SCHEMBL3109628 | 0.75 | SIGMAR1 (0.79) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL9038092 | 0.74 | SIGMAR1 (0.85) | SIGMAR1 | |
| SCHEMBL6560515 | 0.73 | KIF11 (0.42) | SIGMAR1 | |
| SCHEMBL6634044 | 0.72 | SIGMAR1 (0.61) | SIGMAR1KCNH2DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082266-B1 | SUBSTITUTED 1,5-DIAMINOPENTANES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1985-01-09 | — | — | EP | disclosed |
| EP-0082266-A1 | Substituted 1,5-diaminopentanes, their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1983-06-29 | — | — | EP | disclosed |