Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11026189 | 0.93 | SIGMAR1 (0.47) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11027348 | 0.82 | SIGMAR1 (0.47) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL11024413 | 0.82 | SIGMAR1 (0.46) | SIGMAR1KCNH2FDPSDRD3 | |
| SCHEMBL11024266 | 0.77 | SIGMAR1 (0.60) | SIGMAR1KCNH2FDPSDRD2DRD3 | |
| SCHEMBL9639643 | 0.75 | SIGMAR1 (0.64) | SIGMAR1KCNH2FDPSDRD2DRD4 | |
| SCHEMBL10376330 | 0.74 | CYP3A4 (0.61) | KCNH2DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL11021855 | 0.72 | SIGMAR1 (0.54) | SIGMAR1KCNH2FDPSDRD2DRD4 | |
| SCHEMBL737007 | 0.72 | SIGMAR1 (0.83) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL4254894 | 0.72 | SIGMAR1 (1.00) | SIGMAR1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL11022701 | 0.71 | SIGMAR1 (0.53) | SIGMAR1KCNH2FDPSDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082266-B1 | SUBSTITUTED 1,5-DIAMINOPENTANES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1985-01-09 | — | — | EP | disclosed |
| EP-0082266-A1 | Substituted 1,5-diaminopentanes, their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1983-06-29 | — | — | EP | disclosed |