Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Axamozide SCHEMBL11027857 | 0.99 | OPRM1 (0.59) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL11025222 | 0.93 | HTR1A (0.59) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL11100748 | 0.93 | OPRM1 (0.60) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL11023441 | 0.91 | DRD3 (0.58) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL11098294 | 0.90 | OPRM1 (0.62) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL11027738 | 0.90 | HTR1A (0.60) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL11096216 | 0.90 | OPRM1 (0.57) | OPRM1HTR1ADRD2HTR2AHTR2C | |
| SCHEMBL11093124 | 0.89 | OPRM1 (0.58) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL11024054 | 0.89 | DRD2 (0.55) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL11024904 | 0.89 | HTR1A (0.57) | OPRM1CHRM1HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| EP-0068261-B1 | N-OXACYCLYL-ALKYLPIPERIDINE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-03 | — | — | EP | disclosed |