Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | PLD2 | O14939 | 1/20 | 0.51 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11026849 | 0.92 | CHRM1 (0.57) | OPRM1CHRM1DRD3HTR1AADRA2A | |
| SCHEMBL11098879 | 0.90 | OPRM1 (0.58) | OPRM1CHRM1DRD3HTR1ADRD2 | |
| SCHEMBL11103882 | 0.89 | OPRM1 (0.47) | OPRM1CHRM1DRD3HTR1ADRD2 | |
| Axamozide SCHEMBL11022863 | 0.89 | OPRM1 (0.60) | OPRM1CHRM1DRD3HTR1AADRA2A | |
| Axamozide SCHEMBL11027857 | 0.88 | OPRM1 (0.59) | OPRM1CHRM1DRD3HTR1AADRA2A | |
| SCHEMBL11023441 | 0.87 | DRD3 (0.58) | OPRM1CHRM1DRD3HTR1AADRA2A | |
| SCHEMBL11096897 | 0.87 | HTR1A (0.56) | OPRM1CHRM1DRD3HTR1AADRA2A | |
| SCHEMBL11025222 | 0.86 | HTR1A (0.59) | OPRM1CHRM1DRD3HTR1AADRA2A | |
| SCHEMBL11101914 | 0.85 | OPRM1 (0.53) | OPRM1CHRM1DRD3HTR1AADRA2A | |
| SCHEMBL11098935 | 0.85 | HTR1A (0.60) | OPRM1CHRM1DRD3HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470989-A | Neuroleptic n-oxacyclyl-alkylpiperidine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |