Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561687 | 0.82 | CYP2A6 (0.35) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL11019829 | 0.80 | HSP90AA1 (0.41) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL7955333 | 0.79 | ALOX15 (0.46) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL11698172 | 0.78 | SNCA (0.35) | TSHR | |
| SCHEMBL6299216 | 0.78 | PYCR1 (0.47) | PYCR1MAPK1ALDH1A1TSHRMEN1 | |
| SCHEMBL2789656 | 0.77 | PYCR1 (0.44) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL15653274 | 0.76 | PYCR1 (0.32) | PYCR1ALOX15TSHRAHRCYP2A6 | |
| SCHEMBL20560561 | 0.76 | PKM (0.38) | ALDH1A1GPR84MEN1MAPTKMT2A | |
| SCHEMBL22028119 | 0.76 | BACE1 (0.40) | PYCR1ALOX15HSP90AA1ALDH1A1AHR | |
| SCHEMBL14076005 | 0.76 | ALOX15 (0.44) | ALOX15ALDH1A1TSHRHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450298-A | Vapor phase catalytic hydrolysis of benzal chloride or its halogen- or trifluoromethyl-substitute to form benzaldehyde or substitute | CENTRAL GLASS COMPANY, LIMITED (JP) | 1984-05-22 | — | — | US | claimed |
| CN-109111463-A | The manufacturing method of aromatic compound | DIC株式会社 | 2019-01-01 | — | — | CN | disclosed |
| US-4536599-A | HYDROLYZING THE NITRILE DERIVATIVE TO THE AMIDE USING AN ORGANIC QUATERNARY AMINE SALT CATALYST; EFFICIENCY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4450298-A | Vapor phase catalytic hydrolysis of benzal chloride or its halogen- or trifluoromethyl-substitute to form benzaldehyde or substitute | CENTRAL GLASS COMPANY, LIMITED (JP) | 1984-05-22 | — | — | US | disclosed |
| EP-0008532-B1 | SYNTHESIS OF AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-07-20 | — | — | EP | disclosed |
| US-4215220-A | 1-(2-Oxysubstituted-3-anilinopropyl)-imidazoles | CILAG-CHEMIE A.G. (CH) | 1980-07-29 | — | — | US | disclosed |
| EP-0008532-A1 | Synthesis of amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-05 | — | — | EP | disclosed |