Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616819 | 0.81 | CYP2A6 (0.37) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL7955333 | 0.81 | ALOX15 (0.46) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL260670 | 0.81 | CYP2A6 (0.37) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL10831466 | 0.80 | PYCR1 (0.42) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL1539490 | 0.79 | HSP90AA1 (0.42) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL17868540 | 0.79 | S100A4 (0.42) | PYCR1ALOX15HSP90AA1TLR9CYP2A6 | |
| SCHEMBL9171541 | 0.77 | PYCR1 (0.43) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL3373171 | 0.77 | SNCA (0.36) | PYCR1ALOX15ALDH1A1TSHR | |
| SCHEMBL11022982 | 0.77 | PYCR1 (0.43) | PYCR1ALOX15MAPK1TDP1HSP90AA1 | |
| SCHEMBL9171547 | 0.77 | PYCR1 (0.43) | PYCR1ALOX15MAPK1TDP1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480410-A | Synthetic method of 2, 4-dibromobenzyl alcohol | 南京伊派森化学科技有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-103996872-A | Lithium ion battery non-aqueous electrolyte with functions of overcharging prevention and flame retardancy | ZHUHAI SMOOTHWAY ELECTRONIC MATERIALS CO LTD | 2014-08-20 | — | — | CN | claimed |
| CN-114206904-B | Selective BCRP/ABCG2 transporter inhibitors as agents for eliminating resistance to anticancer agents | 格勒诺布尔-阿尔卑斯大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-118344390-A | Polyboronate substituted phenylalanine derivative and preparation method and application thereof | 莆田兰海核医学研究中心 | 2024-07-16 | — | — | CN | disclosed |
| EP-3782996-B1 | NRF2 REGULATORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-04-10 | — | — | EP | disclosed |
| US-20230360922-A1 | ROBUST ASHABLE HARD MASK | LAM RESEARCH CORPORATION | 2023-11-09 | — | — | US | disclosed |
| US-20230242555-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | NEUBORON MEDTECH LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20230242555-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | NEUBORON MEDTECH LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-11655261-B2 | Method for preparing 18F-BPA and intermediate | NEUBORON MEDTECH LTD. (CN) | 2023-05-23 | — | — | US | disclosed |
| US-11655261-B2 | Method for preparing 18F-BPA and intermediate | NEUBORON MEDTECH LTD. (CN) | 2023-05-23 | — | — | US | disclosed |
| US-20230149414-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-18 | — | — | US | disclosed |
| EP-1382607-B1 | Prenyl transferase inhibitors | IPSEN PHARMA (FR) | 2009-08-19 | — | — | EP | disclosed |
| US-20080176835-A1 | Prenyl Transferase Inhibitors | BIOMEASURE, INCORPORATED | 2008-07-24 | — | — | US | disclosed |
| US-7361656-B2 | Prenyl transferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2008-04-22 | — | — | US | disclosed |
| US-7084135-B1 | Prenyl transferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, SAS (FR) | 2006-08-01 | — | — | US | disclosed |
| US-20060142275-A1 | Prenyl transferase inhibitors | IPSEN PHARMA S.A.S. (FR) | 2006-06-29 | — | — | US | disclosed |
| EP-1140942-B1 | PRENYL TRANSFERASE INHIBITORS | CONSEILS DE RECH SET D APPLIC (FR) | 2004-03-10 | — | — | EP | disclosed |
| EP-1382607-A2 | Prenyl transferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-01-21 | — | — | EP | disclosed |
| EP-1140942-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039130-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2000-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176835-A1 | Prenyl Transferase Inhibitors | FNTA, FNTB, RCE1 | PYCR1 2758/4885ALOX15 2656/4885MAPK1 2356/4885 |
| US-20230149414-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | PYCR1 3154/4885ALOX15 3537/4885MAPK1 4411/4885 |
| US-20230242555-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | CYP19A1, SHBG, ESR1 | PYCR1 3051/4885ALOX15 3792/4885MAPK1 3708/4885 |
| US-20060142275-A1 | Prenyl transferase inhibitors | FNTA, FNTB, RCE1 | PYCR1 2758/4885ALOX15 2656/4885MAPK1 2356/4885 |
| US-11655261-B2 | Method for preparing 18F-BPA and intermediate | CYP19A1, SHBG, ESR1 | PYCR1 3051/4885ALOX15 3792/4885MAPK1 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.