Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017667 | 0.88 | MAPK1 (0.49) | PTPRCMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL11022892 | 0.85 | L3MBTL1 (0.49) | PTPRCMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL10678823 | 0.84 | RXRA (0.51) | MAPTKDM4EMAPK1RXRARXRB | |
| SCHEMBL11019719 | 0.83 | KDM4E (0.47) | KDM4EADRB2HTR7THRB | |
| SCHEMBL11021043 | 0.82 | RAB9A (0.50) | PTPRCMAPTMAPK1KMT2AL3MBTL1 | |
| SCHEMBL10525200 | 0.79 | TP53 (0.61) | KDM4ELMNAMAPK1MEN1KMT2A | |
| SCHEMBL11021406 | 0.79 | TP53 (0.61) | KDM4ELMNAMAPK1MEN1KMT2A | |
| SCHEMBL11017378 | 0.79 | TP53 (0.61) | KDM4ELMNAMAPK1MEN1KMT2A | |
| SCHEMBL11021434 | 0.79 | TP53 (0.61) | KDM4ELMNAMAPK1MEN1KMT2A | |
| SCHEMBL11019954 | 0.79 | TP53 (0.61) | KDM4ELMNAMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |