Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435141 | 0.81 | MEN1 (0.70) | MEN1KMT2ACRBNCYP11B1CYP11B2 | |
| SCHEMBL29676340 | 0.80 | KMT2A (0.68) | MEN1KMT2ACRBNCYP11B1CYP11B2 | |
| SCHEMBL7271469 | 0.80 | KMT2A (1.00) | MEN1KMT2ACRBNCYP11B1CYP11B2 | |
| SCHEMBL11028170 | 0.80 | MEN1 (0.73) | MEN1KMT2ACRBNCYP11B1CYP11B2 | |
| SCHEMBL2850811 | 0.80 | MEN1 (0.68) | MEN1KMT2APGRNPC1CYP3A4 | |
| SCHEMBL14114321 | 0.80 | MEN1 (0.68) | MEN1KMT2ACRBNCYP11B1CYP11B2 | |
| SCHEMBL14610310 | 0.80 | MEN1 (0.68) | MEN1KMT2ACRBNCYP11B1CYP11B2 | |
| SCHEMBL7138979 | 0.80 | KMT2A (0.68) | MEN1KMT2ACRBNCYP11B1CYP11B2 | |
| SCHEMBL11027733 | 0.80 | MEN1 (0.68) | MEN1KMT2ACRBNCYP11B1CYP11B2 | |
| SCHEMBL11025336 | 0.78 | MEN1 (0.65) | MEN1KMT2ACRBNCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486040-B1 | AUTOMATED RADIOSYNTHESIS | GE HEALTHCARE LTD (GB) | 2017-06-21 | — | — | EP | disclosed |
| EP-2486040-B1 | AUTOMATED RADIOSYNTHESIS | GE HEALTHCARE LTD (GB) | 2017-06-21 | — | — | EP | disclosed |
| US-8946410-B2 | Automated radiosynthesis | GE HEALTHCARE LIMITED (GB) | 2015-02-03 | — | — | US | disclosed |
| US-20120190843-A1 | AUTOMATED RADIOSYNTHESIS | GE HEALTHCARE LIMITED (GB) | 2012-07-26 | — | — | US | disclosed |
| WO-2011042529-A1 | AUTOMATED RADIOSYNTHESIS | GE HEALTHCARE LIMITED (GB) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190843-A1 | AUTOMATED RADIOSYNTHESIS | GABRB2, GABRB3, GABRR2 | MEN1 2107/4885KMT2A 1636/4885CRBN 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.