SCHEMBL11023908

SCHEMBL11023908

CCCONc1cccc2ccc(O)cc12

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 15/20 0.48
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
ADRA1A P35348 2/20 0.43
MCL1 Q07820 1/20 0.43
ADRA1D P25100 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9807993 0.88 TRPV1 (0.50) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL10584575 0.80 TRPV1 (0.52) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL10484431 0.78 TRPV1 (0.54) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL8017317 0.78 TRPV1 (0.61) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL9816152 0.76 ADRA1A (0.55) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL9816031 0.75 TRPV1 (0.55) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL6583801 0.74 TRPV1 (0.54) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL11722439 0.73 TRPV1 (0.67) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL11492523 0.73 TRPV1 (0.54) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL10794585 0.73 TRPV1 (0.49) TRPV1KDM4EMEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0061670-B1 PROCESS FOR DYEING LEATHER AND PELTS WITH DYE MIXTURES CIBA-GEIGY AG (CH) 1985-06-12 EP disclosed
EP-0009466-A1 1 : 2-Bis-chromium-complex dyestuffs from polyazo- or disazo-azomethine compounds, their preparation and their use CIBA-GEIGY AG (CH) 1980-04-02 EP disclosed