SCHEMBL6583801

SCHEMBL6583801

CNc1cccc2ccc(O)cc12

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 17/20 0.54
MCL1 Q07820 1/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27937958 0.85 TLR8 (0.45) TRPV1MCL1MEN1KMT2A
SCHEMBL11019096 0.82 TRPV1 (0.49) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL9351736 0.81 KEAP1 (0.65) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL9816152 0.80 ADRA1A (0.55) TRPV1MCL1KDM4EMEN1MAPT
SCHEMBL10584575 0.80 TRPV1 (0.52) TRPV1MCL1KDM4EMEN1MAPT
SCHEMBL1413170 0.79 TRPV1 (0.64) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL30125341 0.79 TRPV1 (0.64) TRPV1KDM4EMEN1MAPTRAB9A
Hydrochloric Acid SCHEMBL10348748 0.79 TRPV1 (0.68) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL4649512 0.79 TRPV1 (0.50) TRPV1KDM4EMEN1MAPTRAB9A
Bromide SCHEMBL10348696 0.79 TRPV1 (0.68) TRPV1KDM4EMEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103298772-B Method for producing aromatic alcohol or heterocyclic aromatic alcohol MITSUBISHI GAS CHEMICAL CO 2015-06-24 CN disclosed
CN-103298772-A Method for producing aromatic alcohol or heterocyclic aromatic alcohol MITSUBISHI GAS CHEMICAL CO 2013-09-11 CN disclosed
US-20040259875-A1 Amine derivatives BAYER HEALTHCARE AG (DE) 2004-12-23 US disclosed
EP-1414788-A1 NAPHTHYLUREA AND NAPHTHYLACETAMIDE DERIVATIVES AS VANILLOID RECEPTOR 1 (VR1) ANTAGONISTS Bayer HealthCare AG (DE) 2004-05-06 EP disclosed
WO-2003014064-A1 NAPHTHYLUREA AND NAPHTHYLACETAMIDE DERIVATIVES AS VANILLOID RECEPTOR 1 (VR1) ANTAGONISTS BAYER HEALTHCARE AG (DE) 2003-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259875-A1 Amine derivatives AVPR1A, GRIN1, OPRL1 TRPV1 14/4885MCL1 2609/4885KDM4E 3941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.