SCHEMBL9807993

SCHEMBL9807993

CCONc1cccc2ccc(O)cc12

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 15/20 0.50
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
MCL1 Q07820 1/20 0.45
ADRA1A P35348 2/20 0.45
ADRA1D P25100 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11023908 0.88 TRPV1 (0.48) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL10584575 0.82 TRPV1 (0.52) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL10484431 0.81 TRPV1 (0.54) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL22083437 0.80 KDM4E (0.56) KDM4EMAPTRAB9AKMT2A
SCHEMBL9816152 0.79 ADRA1A (0.55) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL4808201 0.77 ALDH1A1 (0.72) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL6583801 0.76 TRPV1 (0.54) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL10794585 0.76 TRPV1 (0.49) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL4649512 0.74 TRPV1 (0.50) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL9816031 0.74 TRPV1 (0.55) TRPV1KDM4EMEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241414-B1 PROCESS FOR THE PREPARATION OF 1:2 METAL COMPLEX AZO DYES CIBA-GEIGY AG (CH) 1991-05-08 EP disclosed
EP-0241414-A2 Process for the preparation of 1:2 metal complex azo dyes CIBA-GEIGY AG (CH) 1987-10-14 EP disclosed
EP-0185611-A1 Process for the photochemical stabilisation of synthetic fibrous materials containing polyamide fibres CIBA-GEIGY AG (CH) 1986-06-25 EP disclosed
EP-0159962-A2 Fibre-reactive chromium or cobalt complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-10-30 EP disclosed
EP-0142104-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-22 EP disclosed