Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492523 | 0.95 | TRPV1 (0.54) | TRPV1ADRA1AADRA1DKDM4EMAPT | |
| SCHEMBL9816152 | 0.84 | ADRA1A (0.55) | TRPV1ADRA1AADRA1DKDM4EMAPT | |
| SCHEMBL731902 | 0.80 | ALDH1A1 (0.67) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL30301306 | 0.80 | ALDH1A1 (0.67) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL4790558 | 0.79 | CNR1 (0.50) | TRPV1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL4857964 | 0.78 | TLR8 (0.50) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL27467257 | 0.78 | CNR1 (0.56) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL11722439 | 0.78 | TRPV1 (0.67) | TRPV1KDM4EMAPTMEN1RAB9A | |
| SCHEMBL9156403 | 0.77 | NAAA (0.50) | MAPTTSHRMEN1KMT2ATLR8 | |
| SCHEMBL31006472 | 0.76 | IDO1 (0.52) | ADRA1AADRA1DKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255643-B1 | METAL COMPLEX COMPOUND USEFUL AS A NEAR INFRARED ABSORBER | HODOGAYA CHEMICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |
| EP-0099538-B1 | CARBACYCLINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-11 | — | — | EP | disclosed |
| US-4977249-A | FOR OPTICAL FILTERS OR SHIELDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0255643-A2 | Metal complex compound useful as a near infrared absorber | HODOGAYA CHEMICAL CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |