Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022451 | 0.81 | FAAH (0.40) | FAAHALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL2397581 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1LMNAHSD17B10TSHRGABBR2 | |
| SCHEMBL13684719 | 0.79 | GAA (0.40) | ALDH1A1LMNATSHRGABBR2CYP1A2 | |
| SCHEMBL16046274 | 0.78 | FAAH (0.53) | FAAHALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL11020479 | 0.74 | TSHR (0.33) | LMNATSHRGABBR2CYP1A2THPO | |
| SCHEMBL18101453 | 0.73 | FAAH (0.60) | FAAHALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL112407 | 0.73 | CES2 (0.55) | FAAHALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL3018120 | 0.72 | FAAH (0.46) | FAAHALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL10704882 | 0.72 | FAAH (0.69) | FAAHALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL28233813 | 0.72 | FAAH (0.48) | FAAHALDH1A1NPSR1GLO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030424-B1 | DERIVATIVES OF 4-(METHYLPHOSPHINYL)-2-OXOBUTANOIC ACID, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND INTERMEDIATES AND METHODS FOR THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-20 | — | — | EP | claimed |
| EP-0030424-A2 | Derivatives of 4-(methylphosphinyl)-2-oxobutanoic acid, herbicidal compositions containing them, and intermediates and methods for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | claimed |
| US-8481779-B2 | Method for producing N-substituted-2-amino-4-(hydroxymethylphosphinyl)-2-butenoic acid | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20120316358-A1 | METHOD FOR PRODUCING N-SUBSTITUTED-2-AMINO-4-(HYDROXYMETHYLPHOSPHINYL)-2-BUTENOIC ACID | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2012-12-13 | — | — | US | disclosed |
| EP-2522673-A1 | METHOD FOR PRODUCING N-SUBSTITUTED-2-AMINO-4-(HYDROXYMETHYLPHOSPHINYL)-2-BUTENOIC ACID | Meiji Seika Pharma Co., Ltd. (JP) | 2012-11-14 | — | — | EP | disclosed |
| EP-0030424-B1 | DERIVATIVES OF 4-(METHYLPHOSPHINYL)-2-OXOBUTANOIC ACID, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND INTERMEDIATES AND METHODS FOR THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-20 | — | — | EP | disclosed |
| US-4399287-A | POSTEMERGENCE HERBICIDES; PESTICIDES; PLANT GROWTH REGULATORS; DESICCANTS | FBC LIMITED (GB) | 1983-08-16 | — | — | US | disclosed |
| EP-0030424-A2 | Derivatives of 4-(methylphosphinyl)-2-oxobutanoic acid, herbicidal compositions containing them, and intermediates and methods for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316358-A1 | METHOD FOR PRODUCING N-SUBSTITUTED-2-AMINO-4-(HYDROXYMETHYLPHOSPHINYL)-2-BUTENOIC ACID | HSD17B12, DHCR7, HACL2 | FAAH 301/4885ALDH1A1 347/4885NPSR1 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.