Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18037948 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBCYP1A2GAAMGAM | |
| SCHEMBL1108185 | 0.84 | CYP1A2 (0.48) | SMN1; SMN2POLBCYP1A2GAAMGAM | |
| SCHEMBL1556696 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBCYP1A2GAAMGAM | |
| SCHEMBL2397289 | 0.83 | DGKA (0.44) | SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL11806061 | 0.82 | GAA (0.50) | SMN1; SMN2POLBCYP1A2GAAMGAM | |
| SCHEMBL2397915 | 0.80 | DGKA (0.50) | ALDH1A1TSHR | |
| SCHEMBL7716763 | 0.79 | PPARD (0.55) | SMN1; SMN2POLBCYP1A2GAAMGAM | |
| SCHEMBL11023917 | 0.79 | FAAH (0.42) | SMN1; SMN2CYP1A2GAAMGAMSI | |
| SCHEMBL29016532 | 0.79 | ALOX15 (0.47) | SMN1; SMN2POLBCYP1A2GAAMGAM | |
| SCHEMBL2991444 | 0.79 | CYP1A2 (0.44) | SMN1; SMN2POLBCYP1A2GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133356-B1 | PROCESS FOR PRODUCTION OF PHOSPHORUS-CONTAINING -KETO ACID | MEIJI SEIKA PHARMA CO LTD (JP) | 2014-09-24 | — | — | EP | disclosed |
| US-8017797-B2 | Method for producing phosphorus-containing α-keto acid | MEIJI SEIKA KAISHA LTD. (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20100063313-A1 | METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID | MEIJI SEIKA KAISHA LTD., (JP) | 2010-03-11 | — | — | US | disclosed |
| CN-101641363-A | Method for producing phosphorus-containing alpha-keto acid | MEIJI SEIKA KAISHA JP | 2010-02-03 | — | — | CN | disclosed |
| EP-2133356-A1 | PROCESS FOR PRODUCTION OF PHOSPHORUS-CONTAINING -KETO ACID | Meiji Seika Kaisha, Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
| EP-0030424-B1 | DERIVATIVES OF 4-(METHYLPHOSPHINYL)-2-OXOBUTANOIC ACID, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND INTERMEDIATES AND METHODS FOR THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-20 | — | — | EP | disclosed |
| US-4399287-A | POSTEMERGENCE HERBICIDES; PESTICIDES; PLANT GROWTH REGULATORS; DESICCANTS | FBC LIMITED (GB) | 1983-08-16 | — | — | US | disclosed |
| EP-0030424-A2 | Derivatives of 4-(methylphosphinyl)-2-oxobutanoic acid, herbicidal compositions containing them, and intermediates and methods for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063313-A1 | METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID | PRKAB1, PRKAB2, PLCB1 | SMN1; SMN2 4182/4885POLB 193/4885CYP1A2 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.