Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 2/20 | 0.47 |
| ▸ | FNTB | P49356 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453571 | 0.85 | FFAR1 (0.78) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL2226074 | 0.83 | L3MBTL1 (0.68) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL10200947 | 0.80 | GABBR2 (0.64) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL11025431 | 0.79 | AKR1C3 (0.55) | FFAR1L3MBTL1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2452463 | 0.77 | CYP1A2 (0.56) | FFAR1L3MBTL1KMT2AATM | |
| SCHEMBL5720961 | 0.77 | CYP1A2 (0.56) | FFAR1L3MBTL1KMT2AATM | |
| SCHEMBL7104579 | 0.77 | CYP1A2 (0.56) | FFAR1L3MBTL1KMT2AATM | |
| SCHEMBL5702738 | 0.77 | FFAR1 (0.49) | FFAR1L3MBTL1KMT2AATM | |
| SCHEMBL28854188 | 0.77 | FFAR1 (0.59) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL5340895 | 0.76 | L3MBTL1 (0.59) | FFAR1L3MBTL1FNTAFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31980-E | INHIBITOR OF GAMMA-AMINOBUTYRIC ACID TRANSAMINASE | MERRELL TORAUDE ET COMPAGNIE (FR) | 1985-09-03 | — | — | US | disclosed |
| US-4039549-A | INHIBITS CNS TRANSMITTERS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1977-08-02 | — | — | US | disclosed |
| US-3960927-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | RICHARDSON-MERRELL INC. (US) | 1976-06-01 | — | — | US | disclosed |