Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 2/20 | 0.53 |
| ▸ | FNTB | P49356 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226074 | 0.91 | L3MBTL1 (0.68) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL13118253 | 0.89 | FFAR1 (1.00) | FFAR1POLB | |
| SCHEMBL28628025 | 0.87 | FFAR1 (0.59) | FFAR1L3MBTL1KMT2AGAA | |
| SCHEMBL10356759 | 0.87 | FFAR1 (0.62) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL10200947 | 0.85 | GABBR2 (0.64) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL12836590 | 0.85 | FFAR1 (0.59) | FFAR1L3MBTL1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11023933 | 0.85 | FFAR1 (0.60) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL28854188 | 0.84 | FFAR1 (0.59) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL5340895 | 0.83 | L3MBTL1 (0.59) | FFAR1L3MBTL1FNTAFNTBKMT2A | |
| SCHEMBL12174632 | 0.83 | L3MBTL1 (0.86) | FFAR1L3MBTL1KMT2AATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |