Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361466 | 0.77 | ALOX5 (0.49) | S1PR1S1PR3KDM4EHSD17B10ALOX5 | |
| SCHEMBL268758 | 0.77 | L3MBTL1 (0.43) | S1PR1S1PR3KDM4EHSD17B10MEN1 | |
| SCHEMBL29366362 | 0.77 | L3MBTL1 (0.43) | S1PR1S1PR3KDM4EHSD17B10MEN1 | |
| SCHEMBL3190486 | 0.75 | NPSR1 (0.44) | KDM4EHSD17B10NPC1RAB9AMEN1 | |
| SCHEMBL31174130 | 0.73 | CASP3 (0.44) | KDM4EHSD17B10NPC1RAB9AMEN1 | |
| SCHEMBL3830957 | 0.73 | CYP19A1 (0.38) | KDM4EHSD17B10NPC1RAB9AMEN1 | |
| SCHEMBL8040923 | 0.73 | S1PR1 (0.43) | S1PR1S1PR3KDM4EHSD17B10NPC1 | |
| SCHEMBL392622 | 0.72 | CYP11B1 (0.49) | S1PR1KMT2A | |
| SCHEMBL991686 | 0.71 | TP53 (0.47) | KDM4EHSD17B10NPC1RAB9AMAOB | |
| SCHEMBL11467665 | 0.70 | ALOX5 (0.46) | ADORA1ADORA2AALOX5RAB9ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049840-B1 | PROCESS FOR THE PRODUCTION OF RELIEF COPIES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-01-09 | — | — | EP | disclosed |
| US-4421844-A | COMPOUND WHICH SPLITS OFF ACID AND CLEAVABLE ETHER COMPOUND | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-12-20 | — | — | US | disclosed |
| EP-0049840-A2 | Process for the production of relief copies | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-21 | — | — | EP | disclosed |