SCHEMBL11023958

SCHEMBL11023958

CCCC(C(=O)O)(C(=O)OCC)C1CCCCCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CHRM2 P08172 6/20 0.35
CHRM1 P11229 6/20 0.35
CHRM4 P08173 5/20 0.35
CHRM3 P20309 5/20 0.35
SLC6A3 Q01959 2/20 0.34
KCNH2 Q12809 2/20 0.34
CYP2C19 P33261 2/20 0.33
POLB P06746 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7141175 0.93 ALDH1A1 (0.38) ALDH1A1MAPTTHRBATML3MBTL1
SCHEMBL7048060 0.87 ALDH1A1 (0.38) ALDH1A1MAPTTHRBATML3MBTL1
SCHEMBL8330842 0.84 CYP1A2 (0.35) ALDH1A1CHRM2CHRM1CHRM4CHRM3
SCHEMBL26986123 0.84 TSHR (0.39) ALDH1A1MAPTTHRBATML3MBTL1
SCHEMBL8330413 0.84 CASP1 (0.37) ALDH1A1MAPTCHRM2CHRM1CHRM4
SCHEMBL16732287 0.83 ALDH1A1 (0.40) ALDH1A1MAPTTHRBATML3MBTL1
SCHEMBL26986147 0.83 ATM (0.44) ALDH1A1MAPTTHRBATML3MBTL1
SCHEMBL16732009 0.82 KEAP1 (0.36) ALDH1A1CHRM2CHRM1KCNH2CYP1A2
SCHEMBL2323088 0.82 MEN1 (0.35) ALDH1A1MAPTTHRBATML3MBTL1
SCHEMBL16732047 0.81 ALDH1A1 (0.38) ALDH1A1MAPTTHRBATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046961-B1 EPOXY-CYCLOALKYLALKANECARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1985-02-13 EP disclosed
US-4430339-A PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-02-07 US disclosed
WO-1982000822-A1 SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS EISTETTER K 1982-03-18 WO disclosed
EP-0046961-A1 Epoxy-cycloalkylalkanecarboxylic acids, process for their preparation, their use and medicaments containing them Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1982-03-10 EP disclosed