Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330842 | 0.98 | CYP1A2 (0.35) | KEAP1NFE2L2CCR2EPHX1KDM4E | |
| SCHEMBL4581023 | 0.91 | LMNA (0.33) | ALDH1A1CYP1A2HSD17B10LMNA | |
| SCHEMBL4580955 | 0.91 | LMNA (0.33) | ALDH1A1CYP1A2HSD17B10LMNA | |
| SCHEMBL4969315 | 0.83 | ARG1 (0.41) | CCR2EPHX1CYP2D6LMNA | |
| SCHEMBL11023958 | 0.82 | ALDH1A1 (0.36) | KDM4EALDH1A1CYP1A2CHRM2CYP2D6 | |
| SCHEMBL8734148 | 0.82 | KEAP1 (0.38) | KEAP1NFE2L2EPHX1KDM4EALDH1A1 | |
| SCHEMBL16783911 | 0.82 | EPHX2 (0.35) | CCR2EPHX1KDM4EALDH1A1SSTR4 | |
| SCHEMBL16732329 | 0.80 | EPHX2 (0.38) | CCR2EPHX1KDM4EALDH1A1CHRM2 | |
| SCHEMBL8735978 | 0.80 | KEAP1 (0.37) | KEAP1NFE2L2EPHX1KDM4EALDH1A1 | |
| SCHEMBL21269269 | 0.78 | KEAP1 (0.36) | KEAP1NFE2L2EPHX1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2876118-A1 | METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | Toho Titanium CO., LTD. (JP) | 2015-05-27 | — | — | EP | disclosed |