SCHEMBL11024973

SCHEMBL11024973

Cc1ccc(S(=O)(=O)S(=O)(=O)C(Cl)C(=O)[C@@H](N)Cc2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
ALPI P09923 1/20 0.45
PKM P14618 1/20 0.45
PTGS1 P23219 1/20 0.45
XIAP P98170 1/20 0.45
SLC7A5 Q01650 1/20 0.45
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
MAPT P10636 2/20 0.42
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA1 P00915 1/20 0.41
CA4 P22748 1/20 0.41
PLAU P00749 1/20 0.41
HPN P05981 1/20 0.41
SLC15A1 P46059 1/20 0.40
KMT2A Q03164 1/20 0.40
MMP9 P14780 1/20 0.40
ANPEP P15144 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL927264 0.88 ALPI (0.46) GAAALPIPKMPTGS1XIAP
SCHEMBL27084167 0.85 GAA (0.44) GAAALPIPKMPTGS1XIAP
SCHEMBL789966 0.85 GAA (0.44) GAAALPIPKMPTGS1XIAP
SCHEMBL3939051 0.81 GAA (0.44) GAAALPIPKMPTGS1XIAP
SCHEMBL11024971 0.79 GAA (0.44) GAAALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL18191186 0.76 SLC7A5 (0.63) GAAALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL18191199 0.76 SLC7A5 (0.63) GAAALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28023088 0.76 SLC7A5 (0.63) GAAALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10429981 0.76 SLC7A5 (0.63) GAAALPIPKMPTGS1XIAP
SCHEMBL27752802 0.75 MMP9 (0.48) GAAALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230293573-A1 OHPP-FORMULATED NICLOSAMIDE TO TREAT SARS-COV-2, OTHER VIRAL DISEASES, AND CANCERS PURDUE RESEARCH FOUNDATION (US) 2023-09-21 US disclosed
US-10221152-B2 Usage of mycophenolate mofetil or salt thereof in preparing drug for resisting against influenza virus GIANT FORCE TECHNOLOGY CORPORATION (TW) 2019-03-05 US disclosed
CN-103479758-B Sanguisorba officinalis-containing anti-influenza virus pharmaceutical composition 李安荣 2018-02-16 CN disclosed
CN-105246484-B Application of mycophenolate mofetil or salts thereof in preparing anti-influenza virus medicine 当代绿能科技股份有限公司 2017-04-12 CN disclosed
US-20160052905-A1 USAGE OF MYCOPHENOLATE MOFETIL OR SALT THEREOF IN PREPARING DRUG FOR RESISTING AGAINST INFLUENZA VIRUS GIANT FORCE TECHNOLOGY CORPORATION (TW) 2016-02-25 US disclosed
CN-105246484-A Application of mycophenolate mofetil or salts thereof in preparing anti-influenza virus medicine GIANT FORCE TECHNOLOGY CORP 2016-01-13 CN disclosed
CN-103479758-A Sanguisorba officinalis-containing anti-influenza virus pharmaceutical composition LEE AN-RONG 2014-01-01 CN disclosed
US-8414938-B2 Schisandrae fructus extracts for inhibition or prevention of H1N1 influenza virus infection and its application thereof NATIONAL DEFENSE MEDICAL CENTER (TW) 2013-04-09 US disclosed
US-20120189719-A1 SCHISANDRAE FRUCTUS EXTRACTS FOR INHIBITION OR PREVENTION OF H1N1 INFLUENZA VIRUS INFECTION AND ITS APPLICATION THEREOF NATIONAL DEFENSE MEDICAL CENTER (TW) 2012-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10221152-B2 Usage of mycophenolate mofetil or salt thereof in preparing drug for resisting against influenza virus DUSP5, DUSP4, DUSP15 GAA 1732/4885ALPI 272/4885PKM 2635/4885
US-20230293573-A1 OHPP-FORMULATED NICLOSAMIDE TO TREAT SARS-COV-2, OTHER VIRAL DISEASES, AND CANCERS ACE2, TMPRSS2, ACE GAA 2949/4885ALPI 1054/4885PKM 4277/4885
US-20120189719-A1 SCHISANDRAE FRUCTUS EXTRACTS FOR INHIBITION OR PREVENTION OF H1N1 INFLUENZA VIRUS INFECTION AND ITS APPLICATION THEREOF ENGASE, ST3GAL3, NEU1 GAA 729/4885ALPI 2104/4885PKM 2407/4885
US-20160052905-A1 USAGE OF MYCOPHENOLATE MOFETIL OR SALT THEREOF IN PREPARING DRUG FOR RESISTING AGAINST INFLUENZA VIRUS DUSP5, DUSP4, DUSP15 GAA 1732/4885ALPI 272/4885PKM 2635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.