Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024973 | 0.88 | GAA (0.45) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL3939051 | 0.82 | GAA (0.44) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL27752802 | 0.82 | MMP9 (0.48) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL789966 | 0.81 | GAA (0.44) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL27084167 | 0.81 | GAA (0.44) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Dl-Phenylalanine SCHEMBL18191199 | 0.77 | SLC7A5 (0.63) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine SCHEMBL10429981 | 0.77 | SLC7A5 (0.63) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Dl-Phenylalanine SCHEMBL28023088 | 0.77 | SLC7A5 (0.63) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine SCHEMBL18191186 | 0.77 | SLC7A5 (0.63) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL23489731 | 0.76 | MMP9 (0.53) | GAABCHEACHECA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11209440-B2 | T cell balance gene expression, compositions of matters and methods of use thereof | THE BROAD INSTITUTE, INC. | 2021-12-28 | — | — | US | disclosed |
| US-20180187190-A1 | NEW CRISPR ASSAYS | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2018-07-05 | — | — | US | disclosed |
| US-9840532-B2 | 5′-substituted nucleoside compounds | ELI LILLY AND COMPANY (US) | 2017-12-12 | — | — | US | disclosed |
| US-20160377631-A1 | T CELL BALANCE GENE EXPRESSION, COMPOSITIONS OF MATTERS AND METHODS OF USE THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2016-12-29 | — | — | US | disclosed |
| US-20160326208-A1 | 5'-SUBSTITUTED NUCLEOSIDE COMPOUNDS | ELI LILLY AND COMPANY | 2016-11-10 | — | — | US | disclosed |
| US-20130252924-A1 | Compounds and Methods for Treating Pain | AKRON MOLECULES GMBH (AT) | 2013-09-26 | — | — | US | disclosed |
| US-8426150-B2 | Process for differential polypeptides detection and uses thereof | LI RONGXIU (CN) | 2013-04-23 | — | — | US | disclosed |
| US-20110020836-A1 | PROCESS FOR DIFFERENTIAL POLYPEPTIDES DETECTION AND USES THEREOF | LI RONGXIU | 2011-01-27 | — | — | US | disclosed |
| WO-2010133173-A1 | PROCESS FOR DIFFERENTIAL POLYPEPTIDES DETECTION AND USES THEREOF | LI RONGXIU (CN) | 2010-11-25 | — | — | WO | disclosed |
| US-5578477-A | SCREENING FOR ANTICANCER DRUGS, SOURCE OF PURE ENZYME | ARCH DEVELOPMENT CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5173405-A | USE OF ARSENITE TO REVERSIBLY BLOCK STEROID BINDING TO GLUCOCORTICOID RECEPTORS IN THE PRESENCE OF OTHER STEROID RECEPTORS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-12-22 | — | — | US | disclosed |
| WO-1991011713-A1 | ARSENITE USED TO REVERSIBLY BLOCK STEROID BINDING TO GLUCOCORTICOID RECEPTORS IN THE PRESENCE OF OTHER STEROID RECEPTORS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1991-08-08 | — | — | WO | disclosed |
| EP-0320148-A1 | Analogs of fibroblast growth factor | AMGEN INC. (US) | 1989-06-14 | — | — | EP | disclosed |
| WO-1989004832-A1 | ANALOGS OF FIBROBLAST GROWTH FACTOR | AMGEN INC. (US) | 1989-06-01 | — | — | WO | disclosed |
| EP-0263903-A1 | Method for preparing specific inhibitors of virus-specified proteases | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326208-A1 | 5'-SUBSTITUTED NUCLEOSIDE COMPOUNDS | NT5C3B, MCL1, NSUN2 | ALPI 3054/4885PKM 2395/4885PTGS1 3464/4885 |
| US-20130252924-A1 | Compounds and Methods for Treating Pain | TRPV1, ACHE, OPRL1 | ALPI 1890/4885PKM 1281/4885PTGS1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.