Sugi Predict

Sugi Predict / Compounds / SCHEMBL789966

SCHEMBL789966

SCHEMBL789966

Cc1ccc(S(=O)(=O)S(=O)(=O)C(=O)C(Cl)C(=O)[C@@H](N)Cc2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.44
▸ ALPI P09923 1/20 0.43
▸ PKM P14618 1/20 0.43
▸ PTGS1 P23219 1/20 0.43
▸ XIAP P98170 1/20 0.43
▸ SLC7A5 Q01650 1/20 0.43
▸ BCHE P06276 1/20 0.41
▸ ACHE P22303 1/20 0.41
▸ CA2 P00918 3/20 0.40
▸ CA7 P43166 2/20 0.40
▸ CA9 Q16790 2/20 0.39
▸ CA1 P00915 1/20 0.39
▸ CA4 P22748 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ SLC15A1 P46059 1/20 0.39
▸ MMP9 P14780 1/20 0.39
▸ CA12 O43570 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27084167 1.00 GAA (0.44) GAAALPIPKMPTGS1XIAP
SCHEMBL3939051 0.89 GAA (0.44) GAAALPIPKMPTGS1XIAP
SCHEMBL11024973 0.85 GAA (0.45) GAAALPIPKMPTGS1XIAP
SCHEMBL11024971 0.81 GAA (0.44) GAAALPIPKMPTGS1XIAP
SCHEMBL927264 0.81 ALPI (0.46) GAAALPIPKMPTGS1XIAP
SCHEMBL7802309 0.78 ALPI (0.49) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL10352479 0.78 ALPI (0.45) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL30636861 0.77 ALPI (0.50) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1436746 0.75 SLC7A5 (0.63) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7111513 0.75 SLC7A5 (0.63) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240094195-A1 METHOD FOR ASSESSING RESPIRATORY VIRAL INFECTIONS THE UNIVERSITY OF HONG KONG (HK) 2024-03-21 — — US disclosed
US-20240043812-A1 NON-INVASIVE METHOD FOR GENERATING HUMAN THREE-DIMENSIONAL AND TWO- DIMENSIONAL NASOPHARYNGEAL ORGANOIDS CENTRE FOR IMMUNOLOGY & INFECTION LIMITED (HK) 2024-02-08 — — US disclosed
US-9212134-B2 Inhibitors of viral entry into mammalian cells MICROBIOTIX, INC. (US) 2015-12-15 — — US disclosed
US-20130331456-A1 INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS MICROBIOTIX, INC. 2013-12-12 — — US disclosed
EP-2616073-A2 INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS Microbiotix, Inc. (US) 2013-07-24 — — EP disclosed
WO-2013074965-A1 AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS MICROBIOTIX, INC. (US) 2013-05-23 — — WO disclosed
WO-2012037119-A2 INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS MICROBIOTIX, INC. (US) 2012-03-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130331456-A1 INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS HAVCR2, PIGS, ZC3HAV1 GAA 1278/4885ALPI 1218/4885PKM 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.