Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636568 | 0.87 | HSD17B1 (0.59) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL2833531 | 0.81 | KDM4E (0.69) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL969945 | 0.81 | PIK3CA (0.40) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL7631797 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL30457848 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL16636791 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL8043317 | 0.79 | HSD17B1 (0.76) | RAB9ANFKB1NFKB2RELATP53 | |
| SCHEMBL8047555 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1MEN1NPC1MAPT | |
| SCHEMBL8042130 | 0.79 | HSD17B1 (0.46) | KDM4EALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL8045495 | 0.79 | HDAC1 (0.46) | KDM4EALDH1A1MEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050261-B1 | MOULDING MASSES STABILIZED AGAINST THERMOLYSIS WITH A LOW MONOMER CONTENT | BAYER AG (DE) | 1985-08-14 | — | — | EP | disclosed |
| EP-0050261-A1 | Moulding masses stabilized against thermolysis with a low monomer content | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |