Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 12/20 | 0.76 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180710 | 0.87 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9LMNA | |
| SCHEMBL8051392 | 0.81 | HSD17B1 (0.89) | HSD17B1HSD17B2CYP3A4CYP2C9LMNA | |
| SCHEMBL8045495 | 0.79 | HDAC1 (0.46) | HSD17B1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL29431736 | 0.79 | HSD17B1 (0.76) | HSD17B1HSD17B2CYP3A4CYP2C9LMNA | |
| SCHEMBL11324204 | 0.79 | HSD17B1 (0.76) | HSD17B1HSD17B2CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL11025151 | 0.79 | KDM4E (0.49) | HSD17B1TP53POLBNFKB1RAB9A | |
| SCHEMBL8047555 | 0.79 | KDM4E (0.65) | HSD17B1HSD17B2RAB9ASMN1; SMN2 | |
| SCHEMBL8042130 | 0.79 | HSD17B1 (0.46) | HSD17B1TP53POLBNFKB1RAB9A | |
| SCHEMBL9360268 | 0.77 | GAA (0.60) | HSD17B1LMNATP53NFKB1RAB9A | |
| SCHEMBL969040 | 0.77 | ALDH1A1 (0.52) | HSD17B1LMNAPOLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |