Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28238 | 0.93 | GABRA1 (0.32) | — | |
| SCHEMBL17355647 | 0.86 | — | — | |
| SCHEMBL3188810 | 0.86 | ESR1 (0.41) | — | |
| SCHEMBL21304588 | 0.86 | TSHR (0.42) | KIF11 | |
| SCHEMBL15942798 | 0.84 | TSHR (0.46) | — | |
| SCHEMBL11534593 | 0.83 | RAB9A (0.38) | — | |
| SCHEMBL11129516 | 0.83 | HSD11B1 (0.35) | — | |
| SCHEMBL10593649 | 0.83 | — | — | |
| SCHEMBL27653093 | 0.83 | TRPV6 (0.39) | KIF11 | |
| SCHEMBL4022711 | 0.83 | KMT2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083685-B1 | MANUFACTURE OF DIISOCYANATES | AMERICAN CYANAMID COMPANY (US) | 1985-03-06 | — | — | EP | disclosed |
| US-4395369-A | REACTING ISOCYANIC ACID WITH A TERT-ARALLKYL CHLORIDE OR DICHLORIDE IN A SOLVENT; EFFICIENCY | AMERICAN CYANAMID COMPANY (US) | 1983-07-26 | — | — | US | disclosed |