Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Thiosulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosulfuric Acid SCHEMBL167560 | 1.00 | — | — | |
| Thiosulfuric Acid SCHEMBL27794360 | 1.00 | MEN1 (0.39) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL3692088 | 0.95 | MEN1 (0.36) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL3692401 | 0.95 | MEN1 (0.36) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL7451138 | 0.95 | — | — | |
| Thiosulfuric Acid SCHEMBL3691094 | 0.95 | MEN1 (0.36) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL3698555 | 0.95 | MEN1 (0.36) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL3691097 | 0.95 | MEN1 (0.36) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL7904303 | 0.95 | — | — | |
| Thiosulfuric Acid SCHEMBL3687928 | 0.95 | MEN1 (0.36) | MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070143-B1 | ORGANIC THIOSULPHATES AND THIOSULPHONATES USEFUL AS STABILISING AGENTS FOR RUBBER VULCANISATES | MONSANTO EUROPE S.A./N.V. (BE) | 1985-02-20 | — | — | EP | disclosed |
| US-4417012-A | DIENE RUBBER | MONSANTO EUROPE S.A. (BE) | 1983-11-22 | — | — | US | disclosed |
| EP-0070143-A1 | Organic thiosulphates and thiosulphonates useful as stabilising agents for rubber vulcanisates | MONSANTO EUROPE S.A./N.V. (BE) | 1983-01-19 | — | — | EP | disclosed |