Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483267 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPK1MAPTHTT | |
| SCHEMBL11024878 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TDP1MAPK1MAPTLMNA | |
| SCHEMBL7380718 | 0.73 | ALDH1A1 (0.62) | ALDH1A1TDP1MAPK1MAPTHTT | |
| SCHEMBL11027172 | 0.73 | CASP3 (0.43) | ALDH1A1MAPTHTTPOLBL3MBTL1 | |
| SCHEMBL11026369 | 0.72 | L3MBTL1 (0.41) | ALDH1A1MAPK1MAPTHTTNPSR1 | |
| SCHEMBL11029092 | 0.72 | NPC1 (0.46) | ALDH1A1MAPK1MAPTLMNATSHR | |
| SCHEMBL11028408 | 0.72 | IDO1 (0.44) | ALDH1A1MAPTHTTPOLBL3MBTL1 | |
| SCHEMBL11022546 | 0.71 | HCAR2 (0.47) | ALDH1A1HTTLMNATSHRKDM4E | |
| SCHEMBL3785783 | 0.71 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1MAPTHTT | |
| SCHEMBL190434 | 0.71 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479002-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES, PESTICIDES | UNION CARBIDE CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |